Project 4

 

ROS signaling during normal hematopoiesis



Principal Investigator:

Dr. Manuel Grez
Applied Virology and Gene Therapy
Georg-Speyer-Haus Frankfurt/Main

Research Area:

Molecular Virology and Gene Therapy

Summary:

The role of ROS-generating systems and its signal transduction pathways for the physiological regulation of normal hematopoiesis is not well understood. By overexpressing or downmodulating the expression of essential components of the NOX-family of proteins we plan to define the function of NOX-proteins during normal hematopoietic cell proliferation and differentiation.

Links:

Georg-Speyer-Haus, AG Grez (http://www.georg-speyer-haus.de/grps/grppages/aggrez/index.html)