The course of various renal diseases is accompanied by a loss of glomerular visceral epithelial cells (podocytes) followed by a massive proteinuria. The aim of this project is to decipher the complex molecular mechanisms of redox signalling processes that affect the dynamics and permselectivity of the glomerular filtration barrier under physiological and pathophysiological conditions in cultured podocytes and experimental models of glomerulonephritis

Links:

Institute of General Pharmacology and Toxicology (http://www.kgu.de/zpharm/allg/)