Project Overview (TP or Z)


The focus of the initiative is the integrative examination of the redox regulation via oxygen, ROS (reactive oxygen species) and NO (nitric oxide) from the generating systems to functional consequences. Besides the analysis of the formation of redox-active signals, we also investigate the physiological and pathophysiological relevance of these mechanisms concerning cellular and systemic functions. Accordingly, the single projects of the Collaborative Research Center are established in a vertical and mechanistic manner.

For more information please select one of the projects listed above.

Involved facilities

Goethe University Frankfurt, Faculty of Medicine

Preclinical Institutes:
* Institute of Cardiovascular Physiology (Physiology I)
* Institute of Neurophysiology (Physiology II)
* Institute of Biochemistry I (Pathobiochemistry)
* Molecular Bioenergetics
Clinical-Theoretical:
* Institute of General Pharmacology and Toxicology
* Institute of Clinical Pharmacology
* Department of Vascular Matrix Biology
* Institute for Vascular Signalling
Clinical Departments:
* Medical Clinic II: Hematology and Oncology
* Clinic for Anesthesiology, Intensive Care and Pain Therapy

External Institutes

Georg-Speyer-Haus, Frankfurt
* Applied Virology and Gene Therapy